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LEVELS
OF CIRCULATING IGF-1
BLOOD SERUM LEVELS
IGF-1
blood serum levels are the true bio-markers of HGH production in
the body. The following chart indicates the range of IGF-1 blood
serum levels for different age groups.
| Information
Source |
Assays
for Establishing Levels of Circulating HGH |
| Grow
Young with HGH |
IGF-1
(Somatomedin-C) Levels in Blood Serum (in ng/ml) |
| Human
age in years |
0.2-5 |
6-8 |
9-11 |
12-15 |
16-24 |
25-39 |
40-54 |
>55 |
| Mean
values of IGF-1 in ng/ml |
17-248 |
88-474 |
110-565 |
202-957 |
182-780 |
114-492 |
90-360 |
71-290 |
Prior
to the advent of recombinant DNA technology, the only source of
growth hormone was from human cadavers. More than 27,000 children
worldwide were treated with growth hormone of this source (pit-hGH).
Due to short supply, children were treated with low doses and interrupted
schedules. As a result, their response and ultimate height was mitigated.
Distribution of pit-hGH was stopped in the United States and most
of Europe in 1985, with the emergence of Creutzfeldt-Jakob Disease.
This is a rare and fatal spongiform encephalopathy, caused by a
small pathogen called a prion. This is the same pathogen that causes
"Mad Cow Disease" recently seen in Europe from infected
cattle.
It
is impossible to catch Creutzfeldt-Jakob Disease or any other infection
from recombinant human growth hormone because it is not derived
from a human or animal source, but from a purified tissue culture.
For purposes of this discussion, the term growth hormone, GH or
hGH will mean growth hormone made by recombinant DNA technology.
In a paper published by the Journal of American Geriatrics Society
in 1985, endocrinologist the late Daniel Rudman from Madison, Wisconsin
first proposed that the safe new form of HGH could be used to reverse
aging in HGH-deficient individuals.
Since then, numerous HGH studies have been conducted. By repeatedly
having passed controlled, randomized, double-blind studies, HGH
has been proven to prevent or reverse aging's effects.
FOOD SOURCES
HGH
production in the body can be stimulated by oral administration
of HGH precursor Growth Hormone Releasing Agents (GHRA) and IGF-1
simulators: combinations of the amino acids arginine (2-5 g daily)
, ornithine (2-5 g), lysine (1-2 g), and glutamine (2 g).
These amino acids, when taken in the correct combination, preferably
on an empty stomach and just before bedtime, are reported to produce
a significant increase in the circulating HGH. In addition, 2 g
daily gamma-aminobutyric acid (GABA), an amino acid essential for
proper brain function, has been shown to increase the HGH in circulation.
All these supplements should be cycled to allow natural production
of HGH to continue, but cycling recommendations (as well as suggested
daily dosages) vary considerably within the community of scientists
and nutrition experts.
ANTI-AGING CONSIDERATIONS
In
21-year-olds, the normal levels of circulating HGH is approximately
10 milligrams per deciliter of blood; in 61-year-olds, the average
is 2 ml/dl, which represents an 80 percent decrease.
In some cases, older people have circulatory HGH levels that are
less than 10 percent of youthful levels. By age 65, an estimated
50 percent of the population is partially or wholly HGH deficient.
By the time men and women are in their 70s, 38 percent of adults
are as deficient in HGH as growth-stunted children.
Study results indicate that increased circulatory HGH has greater
capacity to prevent and reverse the aging process than any other
substance known to science.
The goal of all forms of HGH replacement therapy is to restore normal
levels to those of early adulthood, for example, to age 30 years.
HGH replacement improves sex drive, sexual performance, fertility,
sperm production, and ovulation. HGH
therapy is more effective when administered in conjunction with
DHEA therapy, as well as estrogen/progesterone replacement for women
and testosterone replacement for men.
Dr. Edmund Chein's Study
One
of the most prominent figures in anti-aging research today is Dr.
Edmund Chein, medical director of the Palm Springs Life Extension
Institute. In 1994, he became the first doctor in the US to openly
offer replacement therapy.
To date, he has treated over 800 people over the age of 40 with
low dose, high frequency treatments. Significantly, 20% of Dr. Chein's
patients are physicians themselves who understand the benefits of
this therapy. Most notably, Dr.
Chein has successfully reversed his own heart disease with this
remediation.
Dr. Chein claims a 100% success rate for his brand of therapy.
He guarantees the following results: a gain in bone density of
1.5%-2.5% every six months; a decrease in body fat of 10%-12%
every six months; and a gain in muscle mass of 8%-10% every six
months. These changes continue until a patient's body composition
mimics that of a 20 year old.
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